If clinical stability allows, the results of these point-of-care hemoglobinometers should be confirmed with a complete blood count, rather than being used as the sole factor in determining transfusion needs during pediatric liver transplantation. A pH/blood gas analyzer (I-STAT Fuso, Osaka, Japan) was used to determine. Hemoglobin (Hb) The i-STAT System provides a calculated hemoglobin result which is determined as follows: hemoglobin (g/dL) hematocrit ( PCV) x 0.34 hemoglobin (g/dL) hematocrit (decimal fraction) x 34 To convert a hemoglobin result from g/dL to mmol/L, multiply the displayed result by 0.621. Median test results were not clinically or statistically different between those measured on the i-STAT and those measured using the manual spun hematocrit reference method (p 0. However, the use of hemoglobin vesicles (HbVs), artificial oxygen carriers. While the HemoCue and iSTAT contribute information in a timely manner during dynamic intraoperative situations, there is significant imprecision compared to the gold standard complete blood count. The i-STAT hematocrit and hemoglobin showed close agreement to comparison methods with minimal bias. Secondary error grid analysis revealed that neither device performed well enough to replace a complete blood count at critical thresholds of hemoglobin values. The mean difference of the HemoCue was 0.4 g/dl ( p < .001) and of the iSTAT was 0.6 g/dl ( p < .001). Resultsīoth point-of-care devices underestimated complete blood count hemoglobin values and neither device satisfied our a priori-defined clinically acceptable level of agreement that 95% of values would fall within ☑ g/dl of the complete blood count measurement. With i-STAT CG8+, healthcare professionals can obtain blood gases, glucose, chemistries, hematocrit and hemoglobin levels in approximately two minutes without leaving the patient’s side. Secondary analyses included an error grid analysis and Cohen's kappa statistic. i-STAT CG8+ Cartridge Providing lab-quality results fast when every minute counts. Agreement between the point-of-care devices and complete blood count was assessed using Bland–Altman analysis, which was the primary outcome. We analyzed 92 contemporaneous pairs of hemoglobin values from the HemoCue and complete blood count, and 252 pairs of hemoglobin values from the iSTAT and complete blood count. We retrospectively collected data from 70 patients presenting for a liver transplant at a single center, tertiary care pediatric hospital over a 3.5-year period. The test for hematocrit, as part of the i-STAT System, is intended for use in the in vitro quantification of packed red blood cell volume fraction in arterial. In this retrospective observational study, we aimed to determine whether 95% of results from two point-of-care hemoglobinometers, the HemoCue and iSTAT, would fall within a difference of ☑ g/dl, our a priori-defined clinically acceptable level of agreement, of the hemoglobin measures on a core laboratory complete blood count. However, the iSTAT-1 results were generally lower than the GenS results, with discrepancies up to 2 g/dL for hemoglobin values and up to 4 for hematocrits at the lowest protein concentration. Point-of-care hemoglobin testing devices play an important role in intraoperative anesthetic management where significant hemorrhage is anticipated however, the reliability of these devices has not been examined in the context of pediatric liver transplantation.
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